Figure 1. Sequencing Chromatogram of pDC-CG DNA. A single extension product was divided into 3 equal aliquots and was cleaned using either Norgen's Sequencing Reaction Clean-Up Kit, or one of two competitor kits.  Sequencing data was then generated using Bigdye Terminator chemistry on the Applied Biosystems 3130xL DNA Sequencer. Panel A corresponds to the results when the sample was cleaned using Competitor 1, and this chromatogram indicates low extension product yields. Panel B corresponds to the results when the sample was cleaned using Competitor 2, and this product exhibited poor dye terminator removal that introduced several blobs to the sequence. Panel C corresponds to the sample cleaned with Norgen’s Sequencing Reaction Clean-Up Kit, and shows good yield and efficient removal of dye terminator and contaminants as indicated from the chromatogram signals.